Centre Publications

Research published by the Centre of Excellence- Treatable Traits investigators are highlighted below. These publications focus on articles that are directly relevant to Treatable Traits in chronic airway diseases.

2022

  1. McDonald VM, Clark VL, Gibson PG, ‘Nothing about us without us- What matters to patients with severe asthma?‘ J Allergy Clin Immunol Practice, Mar 2022. 1016/j.jaip.2021.11.035
  2. Mathioudakis AG, Abroug F, Agustí A, Ananth S, Bakke P, Bartziokas K, et al., ERS statement: a core outcome set for clinical trials evaluating the management of COPD exacerbations. Eur Respir J. May2022 1183/13993003.02006-2021
  3. Thomas D, McDonald VM, Pavord ID, Gibson PG, Asthma remission- what is it and how can it be achieved? Eur Respir J. Mar 2022 1183/13993003.02583-2021
  4. McDonald VM, Gibson PG, Treatable traits in asthma: moving beyond diagnostic labels, Medical Journal of Australia. Apr 2022 5694/mja2.51464
  5. Vertigan AE, Bone SL, Gibson PG, The Impact of Functional Laryngoscopy on the Diagnosis of Laryngeal Hypersensitivity Syndromes, J Allergy Clin Immunol Pract. Feb 2022 1016/j.jaip.2021.10.017
  6. Niessen NM, Fricker M, McDonald VM, Gibson PG, T2-low: What do we know? – Past, present, and future of biologic therapies in non-eosinophilic asthma. Ann Allergy Asthma Immunol, Aug 2022 1016/j.anai.2022.04.020
  7. Denton E, Hew M, Gibson PG, Vertigan A. Lone Ranger or Handpicked Posse? How Multidisciplinary Assessment Helps Evaluate Suspected Laryngeal Disorders, J Allergy Clin Immunol Practice. Feb 2022 1016/j.jaip.2021.11.009
  8. Gibson PG. Caging the coughing canary in the global lung health coal mine, Jan 2022 10.1111/resp.14190
  9. Baggott C, Hardy JK, Sparks J, Sabbagh D, Beasley R, Weatherall M, Fingleton J. Epinephrine (adrenaline) compared to selective beta-2-agonist in adults or children with acute asthma: a systematic review and meta-analysis, Jun 2022 10.1136/thoraxjnl-2021-217124
  10. Cox NS, McDonald CF, Mahal A, Alison JA, Wootton R, Hill CJ, Zanaboni P, O’Halloran P, Bondarenko J, Macdonald H, Barker K, Crute H, Mellerick C, Wageck B, Boursinos H, Lahham A, Nichols A, Czupryn P, Corbett M, Handley E, Burge AT, Holland AE. Telerehabilitation for chronic respiratory disease: a randomised controlled equivalence trial, Thorax. Jul 2022 1136/thoraxjnl-2021-216934
  11. Douglass JA, Lodge C, Chan S, Doherty A, Tan JA, Jin C, Stewart A, Southcott AM, Gillman A, Lee J, Csutoros D, Hannan L, Ruane L, Barnes S, Irving L, Harun NS, Lachapelle P, Spriggs K, Sutherland M, See K, McDonald CF, Conron M, Radhakrishna N, Worsnop C, Johnston FH, Davies JM, Bryant V, Iles L, Ranson D, Spanos P, Vicendese D, Lowe A, Newbigin EJ, Bardin P, Dharmage S. Thunderstorm asthma in seasonal allergic rhinitis: The TAISAR study, Journal of Allergy & Clinical Immunology. May 2022 1016/j.jaci.2021.10.028
  12. Bush A, Pavord ID. Reply to: Challenging the paradigm; moving from umbrella labels to treatable traits in airway disease, Breathe. Mar 2022 1183/20734735.0174-2021
  13.  Melhorn J, Howell I, Pavord ID. Should we apply a treatable traits approach to asthma care? Annals of Allergy, Asthma & Immunology. Apr 2022 1016/j.anai.2022.02.005
  14. Foster J, Beasley R, Braithwaite I, Harrison T, Holliday M, Pavord I, Reddel H. Perspectives of mild asthma patients on maintenance versus as-needed preventer treatment regimens: a qualitative study, BMJ Open. Jan 2022 1136/bmjopen-2020-048537
  15. Thomas D, Gibson PG. Gefapixant for chronic cough, The Lancet. Mar 2022 1016/S0140-6736(21)02438-7
  16. Beasley R, Harrison T, Peterson S, Gustafson P, Hamblin A, Bengtsson T, Fagerås M. Evaluation of Budesonide-Formoterol for Maintenance and Reliever Therapy Among Patients with Poorly Controlled Asthma: A Systematic Review and Meta-analysis, Jama Network Open. Mar 2022 1001/jamanetworkopen.2022.0615

2021

  1. Freitas PD, Passos NFP, Carvalho-Pinto RM, Martins MA, Cavalheri V, Hill K, Stelmach R, Carvalho CRF. A Behaviour Change Intervention Aimed at Increasing Physical Activity Improves Clinical Control in Adults With Asthma: A Randomized Controlled Trial, Jan 2021 10.1016/j.chest.2020.08.2113
  2. Freitas PD, Xavier RF, McDonald VM, Gibson PG, Cordova-Rivera L, Furlanetto KC, et al., Identification of asthma phenotypes based on extrapulmonary treatable traits, Euro Respiratory Journal. Jan 2021 1183/13993003.00240-2020
  3. Fergus W. Gardiner, Alice Richardson, Carly Roxburgh, Marianne Gillam, Leonid Churilov, Ruth McCuaig, Sean Carter, Christopher Arthur, Cynthia Wong, Adam Morton, Leonie Callaway, Karin Lust, Sarah J. Davidson, Katie Foxcroft, Kiri Oates, Lucy Zhang, Sahani Jayawardane, Mathew Coleman, Michael Peek. Characteristics and in-hospital outcomes of patients requiring aeromedical retrieval for pregnancy, compared to non-retrieved metropolitan cohorts, ANZJOG. Jan 2021 1111/ajo.13308
  4. O’Neill C, Gibson PG, Heaney L, Upham JW, Yang I, Reynolds P, Hodge S, Jenkins C, Peters M, Marks GB, James AL, Simpson J. The cost-effectiveness of azithromycin in reducing exacerbations in uncontrolled asthma, Euro Respir J. Feb 2021 1183/13993003.02436-2020
  5. Vertigan AE, Kapela SL, Gibson PG. Laryngeal Dysfunction in Severe Asthma: A Cross-Sectional Observational Study. J Allergy Clin Immunol Pract. Feb 2021 1016/j.jaip.2020.09.034
  6. Vanessa M McDonald, Paola D Urroz, Marika Bajc, Natalie Rutherford, Bree Brooker, Peter G Gibson. Imaging for Precision Medicine: Can V-P SPECT measure Mepolizumab Response in Asthma? Respirology Case Reports. Feb 2021 1002/rcr2.717
  7. Sarah A Hiles, Paola D Urroz, Peter G Gibson, Adam Bogdanovs, Vanessa M McDonald. A feasibility randomised controlled trial of Novel Activity Management in severe ASthma – Tailored Exercise (NAMASTE): Yoga and Mindfulness. BMC Resp Open. Feb 2021 1186/s12890-021-01436-3
  8. Xin Zhang, Li Zhang, Rui Liang, Vanessa M McDonald, Hong Ping Zhang, He Yu, Zong An Liang, Lei Wang, Guy B Marks, Wei Min Li, Gang Wang, Peter G Gibson. Clinical phenotypes of patients hospitalized for an asthma exacerbation: prognostic implications. J Allergy Clin Immunol Pract. Feb 2021 1016/j.jaip.2020.09.031
  9. Hew M, Denton E. Prioritizing Treatable Traits in Airways Disease. J Allergy Clin Immunol Pract. Mar 2021 1016/j.jaip.2020.11.012
  10. Sarah A. Hiles, Peter G. Gibson, Alvar Agustí, Vanessa M. McDonald. Treatable Traits That Predict Health Status and Treatment Response in Airway Disease. J Allergy Clin Immunol Pract. Mar 2021 1016/j.jaip.2020.09.046
  11. Robijn AL, Barker D, Gibson PG, Giles WB, Clifton VL, Mattes J, Peek MJ, Barrett HL, Seeho SK, Callaway LK, Abbott A, Attia J, Wark PA, Jensen ME, Murphy VE. Factors Associated with Nonadherence to Inhaled Corticosteroids for Asthma During Pregnancy. J Allergy Clin Immunol Pract. Mar 2021 1016/j.jaip.2020.09.045
  12. Natasha Winter, Peter G Gibson, Michael Fricker, Jodie L Simpson, Peter AB Wark, Vanessa M McDonald. Hemopexin: a novel anti-inflammatory diagnostic marker in chronic airway disease. Allergy Asthma Immunol Res. May 2021 4168/aair.2021.13.3.450
  13. Laura Cordova-Rivera, Paul A.Gardiner, Peter G.Gibson, Elisabeth A.H.Winkler, Paola D.Urroz, Vanessa M.McDonald. Sedentary time in people with obstructive airway diseases. Respiratory Medicine. May 2021 1016/j.rmed.2021.106367
  14. McDowell PJ, Diver S, Yang F, Borg C, Busby J, Brown V, Shrimanker R, Cox C, Brightling CE, Chaudhuri R, Pavord ID, Heaney LG; Medical Research Council: Refractory Asthma Stratification Programme (RASP-UK Consortium). The inflammatory profile of exacerbations in patients with severe refractory eosinophilic asthma receiving mepolizumab (the MEX study): a prospective observational study. Lancet Respiratory Medicine. May 2021 1016/S2213-2600(21)00004-7
  15. Pham J, Hew M, Dharmage SC. Is ethnicity a ‘treatable trait’ in asthma? Jun 2021 10.1111/resp.14058
  16. Gibson PG, Prazma CM, Chupp GL, Bradford ES, Forshag M, Mallett SA, Yancey SW, Smith SG, Bel EH. Mepolizumab improves clinical outcomes in patients with severe asthma and comorbid conditions. Respiratory Medicine. Jun 2021 1186/s12931-021-01746-4
  17. Murphy RC, Pavord ID, Alam R, Altman MC. Management Strategies to Reduce Exacerbations in non-T2 Asthma. J Allergy Clin Immunol. Jul 2021 1016/j.jaip.2021.04.033
  18. Michael Fricker, Vanessa M. McDonald, Natasha A. Winter, Katherine J. Baines, Peter A.B. Wark, Jodie L. Simpson, Peter G. Gibson. Molecular markers of type 2 airway inflammation are similar between eosinophilic severe asthma and eosinophilic COPD. Allergy. Jul 2021 1111/all.14741
  19. Shukla SD, Taylor SL, Gibson PG, Barker D, Upham JW, Yang IA, Reynolds PN, Hodge S, James AL, Rogers GB, Simpson JL. Add-on azithromycin reduces sputum cytokines in non-eosinophilic asthma: an AMAZES substudy. Thorax. Jul 2021 1136/thoraxjnl-2020-216331
  20. Murphy VE, Karmaus W, Mattes J, Brew BK, Collison A, Holliday E, Jensen ME, Morgan GG, Zosky GR, McDonald VM, Jegasothy E, Robinson PD, Gibson PG. Exposure to Stress and Air Pollution from Bushfires during Pregnancy: Could Epigenetic Changes Explain Effects on the Offspring? Int J Environ Res Public Health. Jul 2021 3390/ijerph18147465
  21. Niessen N, Gibson P, K.J. B, Barker D, Yang I, Upham J, P. R, Hodge S, James A, Jenkins C, Peters M, Mark G, Baraket M, Simpson J, Fricker M. Sputum TNF markers are increased in neutrophilic and severe asthma and are reduced by azithromycin treatment. Allergy. Jul 2021 1111/all.14768
  22. Wen Wen Wu, Xin Zhang, Min Li, Ying Liu, Zhi Hong Chen, Min Xie, Shu Zhen Zhao, Gang Wang, Hong Ping Zhang, Ting Wang, Ling Qin, Lei Wang, Brian G. Oliver, Hua Jing Wan, Jie Zhang, Vanessa M. McDonald, Guy B. Marks, Wei Min Li, Surinder S. Birring, Gang Wang, Peter G. Gibson. Treatable Traits in Elderly Asthmatics from the Australasian Severe Asthma Network: A Prospective Cohort Study. J Allergy Clin Immunol Pract. Jul 2021 1016/j.jaip.2021.03.042
  23. Natasha A Winter, Ling Qin, Peter G Gibson, Vanessa M McDonald, Katherine J Baines, Jack Faulkner, Tiffany Evans, Michael Fricker. Sputum mast cell/basophil gene expression relates to inflammatory and clinical features of severe asthma. Journal of Clinical Immunology. Aug 2021 1016/j.jaci.2021.01.033
  24. Couillard S, Laugerud A, Jabeen M, Ramakrishnan S, Melhorn J, Hinks T, Pavord I. Derivation of a prototype asthma attack risk scale centred on blood eosinophils and exhaled nitric oxide. Thorax. Aug 2021 1136/thoraxjnl-2021-217325
  25. Jorge F Maspero, John Mark FitzGerald, Ian D Pavord, Megan S Rice, Jaman Maroni, Paul J Rowe, Gianluca Pirozzi, Nikhil Amin, Marcella Ruddy, Neil M H Graham, Ariel Teper, Megan Hardin. Dupilumab efficacy in adolescents with uncontrolled, moderate-to-severe asthma: LIBERTY ASTHMA QUEST. Allergy. Aug 2021 1111/all.14872
  26. Gang Wang, Vanessa M McDonald. Contemporary Concise Review 2020: Asthma. Respirology. Aug 2021 1111/resp.14099
  27. Agustí A, Barnes N, Cruz AA, Gibson PG, Heaney LG, Inoue H, Leather D, Martinez FJ, McDonald VM, Oppenheimer J, Papi A, Pavord ID, Thomas M, Walker S, Yates L. Moving towards a Treatable Traits model of care for the management of obstructive airways diseases. Respiratory Medicine. Aug 2021 1016/j.rmed.2021.106572
  28. Bokern MP, Robijn AL, Jensen ME, Barker D, Callaway L, Clifton V, Wark P, Giles W, Mattes J, Peek M, Attia J, Seeho S, Abbott A, Gibson PG, Murphy VE. Risk Factors Associated with Asthma Exacerbations During Pregnancy: protocol for a systematic review and meta-analysis. J Allergy Clin Immunol Pract. Aug 2021 (online ahead of print) 1186/s13643-022-01975-8
  29. Michael Fricker, Ling Qin, Stephany Sánchez-Ovando, Jodie L Simpson, Katherine J Baines, Carlos Riveros, Hayley A Scott, Lisa G Wood, Peter AB Wark, Nazanin Z Kermani, Kian Fan Chung, Peter G Gibson. An altered sputum macrophage transcriptome contributes to the neutrophilic asthma endotype. Allergy Sept 2021 1111/all.15087
  30. Gibson PG, McDonald VM, Granchelli A, Olin JT. Asthma and Comorbid Conditions – Pulmonary Comorbidity. J Allergy Clin Immunol Pract. Sept 2021 1016/j.jaip.2021.08.028
  31. Lugogo N, Liu MC, Pavord I, Mitchell PD, Smith SG, Mallett S, Albers FC, Bradford ES, Yancey SW, Bel EH. Clinical effects of mepolizumab in patients with severe eosinophilic asthma according to background therapy: A meta-analysis. J Allergy Clin Immunol Pract. Sept 2021 1016/j.jaip.2021.05.024
  32. Busby J, Matthews JG, Chaudhuri R, Pavord ID, Hardman TC, Arron JR, Bradding P, Brightling CE, Choy DF, Cowan DC, Djukanovic R, Hanratty CE, Harrison TW, Holweg CT, Howarth PH, Fowler SJ, Lordan JL, Mansur AH, Menzies-Gow A, Niven RM, Robinson DS, Walker SM, Woodcock A, Heaney LG; investigators for the MRC Refractory Asthma Stratification Program. Factors affecting adherence with treatment advice in a clinical trial of patients with severe asthma. Eur Respir J. Sept 2021 1183/13993003.00768-2021
  33. Blakey J, Chung LP, McDonald VM, Ruane L, Gornall J, Barton C, Bosnic-Anticevich S, Harrington J, Hew M, Holland AE, Hopkins T, Jayaram L, Reddel H, Upham JW, Gibson PG, Bardin P. Oral corticosteroids stewardship for asthma in adults and adolescents: A position paper from the Thoracic Society of Australia and New Zealand. Respirology. Sept 2021 1111/resp.14147
  34. Risa Fukusho, Laurence Ruane, Debra Phyland, Joo Koh, Adriana Avram, Paul Leong,Martin MacDonald, Kenneth K Lau, Malcolm Baxter, Philip G Bardin.  A Multidisciplinary Team Clinic for Vocal Cord Dysfunction reduces Corticosteroid burst therapy. Journal of Allergy and Clinical Immunology: In Practice. Oct 2021 1016/j.jaip.2021.10.039
  35. Upham JW, Le Lievre C, Jackson DJ, Masoli M, Wechsler ME, Price DB; Delphi Panel. Defining a Severe Asthma Super-Responder: Findings from a Delphi Process. Journal of Allergy and Clinical Immunology: In Practice. Nov 2021. 1016/j.jaip.2021.06.041
  36. Vertigan AE, Bone, SL., Gibson PG. The impact of functional laryngoscopy on the diagnosis of laryngeal hypersensitivity syndromes. Journal of Allergy and Clinical Immunology: In Practice. In Press 2021 1016/j.jaip.2021.10.017
  37. Leong P, Phyland DJ, Koo J, Baxter M, Bardin PG. Middle Airway Obstruction: Phenotyping Vocal Cord Dysfunction/Inducible Laryngeal Obstructions. Lancet Respiratory Medicine. Accepted 2021 1016/S2213-2600(21)00501-4
  38. Upham JW, Le Lievre C, Jackson DJ, Masoli M, Wechsler ME, Price DB; Delphi Panel. Defining a Severe Asthma Super-Responder: Findings from a Delphi Process. J Allergy Clin Immunol Practice. Nov 2021 1016/j.jaip.2021.06.041
  39. Duszyk K, McLoughlin RF, Gibson PG, McDonald VM. The use of treatable traits to address COPD complexity and heterogeneity and to inform the care, Breathe. Dec 2021 1183/20734735.0118-2021
  40. Mallise CA, Murphy VE, Karayanidis F, Armstrong H, Whalen OM, Woolard AJ, Gibson PG, Mattes J, Collison A, Lane AE, Campbell LE. Parenting stress in mothers with asthma during the postpartum period. Journal of Asthma. Nov 2021 1080/02770903.2021.1993246
  41. Shaw DE, Heaney LG, Thomas M, Beasley R, Gibson PG, Pavord ID. Balancing the needs of the many and the few: where next for adult asthma guidelines? Lancet Respir Med. Jul 2021 1016/S2213-2600(21)00021-7
  42. Stubbs MA, Clark VL, Cheung MMY, Smith L, Saini B, Yorke J, Majellano EC, Gibson PG, McDonald VM. The Experience of Living with Severe Asthma, Depression & Anxiety: A Qualitative Art-Based Study, Journal of Asthma & Allergy. Dec 2021 2147/JAA.S328104
  43. Da Silva Sena CR, de Queiroz Andrade E, de Gouveia Belinelo P, Percival E, Prangemeier B, O’Donoghue C, Terry S, Burke T, Gunning W, Murphy VE, Robinson PD, Sly PD, Gibson PG, Collison AM, Mattes J. Higher exhaled nitric oxide at 6 weeks of age is associated with less bronchiolitis and wheeze for the 12 months of age, Thorax. Dec 2021 1136/thoraxjnl-2021-217299
  44. Duszyk K, McLoughlin RF, Gibson PG, McDonald VM. The use of treatable traits to address COPD complexity and heterogeneity and to inform the care, Breathe. Dec 2021 1183/20734735.0118-2021
  45. Stubbs MA, Clark VL, Cheung MMY, Smith L, Saini B, Yorke J, Majellano EC, Gibson PG, McDonald VM. The Experience of Living with Severe Asthma, Depression & Anxiety: A Qualitative Art-Based Study, Journal of Asthma & Allergy. Dec 2021 2147/JAA.S328104
  46. Shaw DE, Heaney LG, Thomas M, Beasley R, Gibson PG, Pavord ID. Balancing the needs of the many and the few: where next for adult asthma guidelines? Lancet Respir Med. Jul 2021 1016/S2213-2600(21)00021-7
  47. Mallise CA, Murphy VE, Karayanidis F, Armstrong H, Whalen OM, Woolard AJ, Gibson PG, Mattes J, Collison A, Lane AE, Campbell LE. Parenting stress in mothers with asthma during the postpartum period. Journal of Asthma. Nov 2021 1080/02770903.2021.1993246
  48. Da Silva Sena CR, de Queiroz Andrade E, de Gouveia Belinelo P, Percival E, Prangemeier B, O’Donoghue C, Terry S, Burke T, Gunning W, Murphy VE, Robinson PD, Sly PD, Gibson PG, Collison AM, Mattes J. Higher exhaled nitric oxide at 6 weeks of age is associated with less bronchiolitis and wheeze for the 12 months of age, Thorax. Dec 2021 1136/thoraxjnl-2021-217299
  49. Vertigan AE, Kapela SL, Birring SS, Gibson PG. Feasibility, and clinical utility of ambulatory cough monitoring in an outpatient clinical setting: a real-world retrospective evaluation, ERJ Open Research. Oct 2021 1183/23120541.00319-2021
  50. Foster PS, Barnes JL, Tay HL, Gibson PG. Transcriptomic drug-response gene signatures are informative for the stratification of patients for clinical trials, Journal of Allergy & Clinical Immunology. Jan 2021 1016/j.jaci.2021.09.021
  51. Williams C, Johnson B, Middleton PG, Backer V, Gibson PG, Hollis G, Coleman C. Family planning, pregnancy, and birth in women with lung conditions: a worldwide survey, ERJ Open Research. Dec 2021 1183/23120541.00357-2021
  52. Ali H, Brooks C, Crane J, Beasley R, Holgate S, Gibson P, Pattemore P, Tzeng YC, Stanley T, Pearce N, Douwes J. Enhanced airway sensory nerve reactivity in non-eosinophilic asthma, BMJ Journals 1136/bmjresp-2021-000974
  53. Harvey SM, Murphy VE, Whalen OM, Gibson PG, Jensen ME. Breastfeeding and wheeze-related outcomes in high-risk infants: A systematic review and meta-analysis, American Journal of Clinical Nutrition. Nov 2021 1093/ajcn/nqaa442
  54. de Gouveia Belinelo P, Collison AM, Murphy VE, Robinson PD, Jesson K, Hardaker K, de Queiroz Andrade E, Oldmeadow C, Martins Costa Gomes G, Sly PD, Usemann J, Appenzeller R, Gorlanova O, Fuchs O, Latzin P, Gibson PG, Frey U, Mattes J. Maternal asthma is associated with reduced lung function in male infants in a combined analysis of the BLT and BILD cohorts, Thorax. Oct 2021 1136/thoraxjnl-2020-215526
  55. Bondarenko J, Babic C, Burge AT, Holland AE. Home-based pulmonary rehabilitation: an implementation study using the RE-AIM framework, ERJ Open Research. May 2021 1183/23120541.00469-2020
  56. Shaw DE, Heaney LG, Thomas M, Beasley R, Gibson PG, Pavord ID, Balancing the needs of the many and the few: where next for adult asthma guidelines? The Lancet Respiratory Medicine. Jul 2021 1016/S2213-2600(21)00021-7
  57. O’Byrne PM, Reddel HK, Beasley R. The management of mild asthma, Euro Respiratory Journal. Apr 2021 1183/13993003.03051-2020
  58. Beasley R, Bruce P, Hatter L, Braithwaite I, Semprini A, Kearns C, Weatherall M, Pavord ID. A Proposed Revision of the Stepwise Treatment Algorithm in Asthma. American Journal of Respiratory and Critical Care Medicine. Jul 2021 1164/rccm.202101-0224LE
  59. Rogliani P, Beasley R, Cazzola M, Calzetta L. SMART for the treatment of asthma: A network meta-analysis of real-world evidence, Respiratory Medicine. Nov 2021 1016/j.rmed.2021.106611
  60. Reddel HK, Vestbo J, Agustí A, Anderson GP, Bansal AT, Beasley R, Bel EH, Janson C, Make B, Pavord ID, Price D, Rapsomaniki E, Karlsson N, Finch DK, Nuevo J, de Giorgio-Miller A, Alacqua M, Hughes R, Müllerová H, Gerhardsson de Verdier M, NOVELTY study investigators. Heterogeneity within and between physician-diagnosed asthma and/or COPD: NOVELTY cohort, Euro Respiratory Journal. Sep 2021 1183/13993003.03927-2020
  61. Bush A, Dalziel SR, Byrnes CA, Hatter L, Beasley R. Has the time come to end use of the blue inhaler? Lancet Respir Med. Jun 2021 1016/S2213-2600(21)00185-5 Braithwaite IE, Cai F, Tom JA, Galanter JM, Owen RP, Zhu R, Williams M, McGregor AG, Eliahu A, Durk MR, Dengler HS, Zak M, Kenny JR, Wilson ME, Beasley R, Chen H. Inhaled JAK inhibitor GDC-0214 reduces exhaled nitric oxide in patients with mild asthma: A randomized, controlled, proof-of-activity trial, Journal of Allergy & Clinical Immunology. Sep 2021 1016/j.jaci.2021.02.042 Lahham A, Holland AE. The Need for Expanding Pulmonary Rehabilitation Services, Life (Basel). Nov 2021 3390/life11111236
  62. Bush A, Pavord ID. Challenging the paradigm: moving from umbrella labels to treatable traits in airway disease, Breathe. Sep 2021 1183/20734735.0053-2021 Malaguti C, Holland AE, McDonald CF, Mahal A, Alison JA, Hill CJ, Zanaboni P, O’Halloran P, Bondarenko J, Macdonald H, Barker K, Crute H, Mellerick C, Wageck B, Boursinos H, Lahham A, Nichols A, Czupryn P, Burge AT, Cox NS. Community Participation by People with Chronic Obstructive Pulmonary Disease, COPD Journal. Oct 2021 1080/15412555.2021.1966761
  63. Couillard S, Do WIH, Beasley R, Hinks TSC, Pavord ID. Predicting the benefits of type-2 targeted anti-inflammatory treatment with the prototype Oxford Asthma Attack Risk Scale (ORACLE), ERJ Open Research. Feb 2021 1183/23120541.00570-2021
  64. Burge AT, Rodrigues JC Jr, Abramson MJ, Cox NS, Bondarenko J, Webb E, Marceau T, Handley E, Macdonald H, Askin A, Calasans GASA, do Amaral DP, Dreger J, Dal Corso S, Holland AE. Application of the Modified Incremental Step Test for Pulmonary Rehabilitation, Physical Therapy & Rehabilitation Journal. May 2021 1093/ptj/pzab044
  65. José A, Holland AE, Selman JPR, de Camargo CO, Fonseca DS, Athanazio RA, Rached SZ, Cukier A, Stelmach R, Dal Corso S. Home-based pulmonary rehabilitation in people with bronchiectasis: a randomised controlled trial, ERJ Open Research. May 2021 1183/23120541.00021-2021
  66. Green ET, Cox NS, Holland AE. A Brief Intervention of Physical Activity Education and Counselling in Community Rehabilitation: A Feasibility Randomized Controlled Trial. Journal of Ageing & Physical Activity. Dec 2021 1123/japa.2021-0256
  67. Cox NS, Scrivener K, Holland AE, Jolliffe L, Wighton A, Nelson S, McCredie L, Lannin NA. A Brief Intervention to Support Implementation of Telerehabilitation by Community Rehabilitation Services During COVID-19: A Feasibility Study, American Congress of Rehabilitation Medicine. Apr 2021 1016/j.apmr.2020.12.007
  68. Malaguti C, Dal Corso S, Janjua S, Holland AE. Supervised maintenance programmes following pulmonary rehabilitation compared to usual care for chronic obstructive pulmonary disease, Cochrane Library. Aug 2021 1002/14651858.CD013569.pub2
  69. Khor YH, Dudley KA, Herman D, Jacobs SS, Lederer DJ, Krishnan JA, Holland AE, Ruminjo JK, Thomson CC. Summary for Clinicians: Clinical Practice Guideline on Home Oxygen Therapy for Adults with Chronic Lung Disease, Annals of the American Thoracic Society. Sep 2021 1513/AnnalsATS.202102-165CME
  70. Dennett EJ, Janjua S, Stovold E, Harrison SL, McDonnell MJ, Holland AE. Tailored or adapted interventions for adults with chronic obstructive pulmonary disease and at least one other long-term condition: a mixed methods review, Cochrane Library. Jul 2021 1002/14651858.CD013384.pub2  
  71. Burge AT, Holland AE, McDonald CF, Hill CJ, Lee AL, Cox NS, Moore R, Nicolson C, O’Halloran P, Lahhama A, Gillies R, Mahald A. “Willingness to Pay”: The Value Attributed to Program Location by Pulmonary Rehabilitation Participants, COPD Journal. Jun 2021: 1080/15412555.2021.1924127
  72. AlQuran A, Batra M, Harry Susanto N, Holland AE, Davies JM, Erbas B, Lampugnani ER. Community Response to the Impact of Thunderstorm Asthma Using Smart Technology, Allergy & Rhinology. Apr 2021 1177/2152656721101072
  73. Smallwood N, Holland AE. Over-oxygenation in the acute hospital setting: an implementation failure in need of an implementation science solution, Internal Medicine Journal. May 2021 1111/imj.15326
  74. Cox NS, McDonald CF, Gleeson M, Wood L, Hall S, Hill C, Bondarenko J, Holland AE. Challenges of evaluating the effect of exercise training on salivary IgA in people with COPD The Clinical Respiratory Journal. Jun 2021 1111/crj.13337
  75. Kimmel LA, Burge A, Watterson D, Wolters C, Holland A, Reed M, Hunter P, Brookes B, Lee V, Leong R. Substituting inpatient rehabilitation beds for home-based multidisciplinary rehabilitation: A qualitative study of patient perceptions, Australasian Journal on Ageing. Sep 2021 1111/ajag.12883
  76. Bondarenko J, Hew M, Button B, Webb E, Jackson V, Clark R, Holland AE. Reliability of the breathing pattern assessment tool for in-person or remote assessment in people with asthma, Clinical & Experimental Allergy. Sep 2021 1111/cea.13856 Leong P, Bardin PG. The untreated treatable trait: Cardiovascular disease in COPD exacerbations, Respirology. May 2021 1111/resp.14036
  77. Bardin PG. Breathing-swallow dysfunction in COPD: How silent aspiration may be contributing to exacerbations, Official Journal of the Asian Pacific Society of Respirology. Dec 2021 1111/resp.14157
  78. Cvejic L, Guiney N, Lau KK, Finlay P, Hamza K, Leong P, MacDonald M, King PT, Bardin PG. Swallow patterns associated with aspiration in COPD: a prospective analysis, ERJ Open Research. Jul 2021 1183/23120541.00170-2021

2020

  1. Thomas, Dennis; McDonald, Vanessa M.; Simpson, Jodie L.; Smith, Amber; Gupta, Sachin; Majellano, Eleanor; Gibson, Peter G. Patterns of azithromycin use in obstructive airway diseases: a real-world observational study. Internal Medicine Journal https://onlinelibrary.wiley.com/doi/10.1111/imj.15216
  2. Thomas, Dennis; Harvey, Erin; McDonald, Vanessa M.; Stevens, Sean; Upham, John W.; Katelaris, Constance H.; Kritikos, Vicky; Gillman, Andrew; Harrington, John; Hew, Mark; Bardin, Philip; Peters, Matthew; Reynolds, Paul N.; Langton, David; Baraket, Melissa; Bowden, Jeffrey J.; Bowler, Simon; Chien, Jimmy; Chung, Li Ping; Farah, Claude S.; Grainge, Christopher; Jenkins, Christine; Katsoulotos, Gregory P.; Lee, Joy; Radhakrishna, Naghmeh; Reddel, Helen K.; Rimmer, Janet; Sivakumaran, Pathmanathan; Wark, Peter A. B.; Gibson, Peter G. Mepolizumab and oral corticosteroid stewardship – data from Australian Mepolizumab Registry The Journal of Allergy and Clinical Immunology: In Practice https://www.sciencedirect.com/science/article/pii/S2213219821001562?via%3Dihub
  3. McDonald VM, Clark VL, Cordova-Rivera L, Wark PAB, Baines KJ, Gibson PG. Targeting treatable traits in severe asthma: a randomised controlled trial. Eur Respir J https://erj.ersjournals.com/content/55/3/1901509.long
  4. Sarah A Hiles, Paola D Urroz, Peter G Gibson, Adam Bogdanovs, Vanessa M McDonald. A feasibility randomised controlled trial of Novel Activity Management in severe ASthma – Tailored Exercise (NAMASTE): Yoga and Mindfulness. BMC Resp Open https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890-021-01436-3
  5. Muhammad Rehan Sarwar, Vanessa Marie McDonald, Michael John Abramson, Eldho Paul, Johnson George. Treatable traits in an English cohort: prevalence and predictors of future decline in lung function and quality of life in COPD. ERJ Open Research https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165376/
  6. Clark VL, Gibson PG, McDonald VM. The patients’ experience of severe asthma add-on pharmacotherapies; a qualitative descriptive study’. Journal of Asthma and Allergy. https://www.dovepress.com/the-patientsrsquo-experience-of-severe-asthma-add-on-pharmacotherapies-peer-reviewed-fulltext-article-JAA
  7. Natasha A Winter, Ling Qin, Peter G Gibson, Vanessa M McDonald, Katherine J Baines, Jack Faulkner, Tiffany Evans, Michael Fricker. Sputum mast cell/basophil gene expression relates to inflammatory and clinical features of severe asthma. Journal of Clinical Immunology https://www.jacionline.org/article/S0091-6749(21)00222-0/fulltext
  8. Vanessa M McDonald, Paola D Urroz, Marika Bajc, Natalie Rutherford, Bree Brooker, Peter G Gibson. Imaging for Precision Medicine: Can V-P SPECT measure Mepolizumab Response in Asthma? Respirol Case Rep https://onlinelibrary.wiley.com/doi/full/10.1002/rcr2.717
  9. Eleanor C Majellano, Vanessa L Clark, Juliet M Foster, Peter G Gibson, Vanessa M McDonald. It’s like being on a roller coaster: The burden of caring for people with severe asthma. ERJ Open Research. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039902/
  10. Michael Fricker, Vanessa M. McDonald, Natasha A. Winter, Katherine J. Baines, Peter A.B. Wark, Jodie L. Simpson, Peter G. Gibson. Molecular markers of type 2 airway inflammation are elevated in eosinophilic severe asthma, but not in eosinophilic COPD. Allergy. https://onlinelibrary.wiley.com/doi/10.1111/all.14741
  11. Patricia D Freitas, Rafaela F Xavier, Vanessa M McDonald, Peter G Gibson, Laura Cordova-Rivera, Karina C Furlanetto, Joice M de Oliveira, Regina M Carvalho-Pinto, Alberto Cukier, Rafael Stelmach, Celso R F Carvalho. Identification of asthma phenotypes based on extrapulmonary traits; physical activity, psychosocial distress and obesity. Eur Respir J. https://erj.ersjournals.com/content/57/1/2000240.long
  12. Xin Zhang, Li Zhang, Rui Liang, Vanessa M McDonald, Hong Ping Zhang, He Yu, Zong An Liang, Lei Wang, Guy B Marks, Wei Min Li, Gang Wang, Peter G Gibson. Clinical phenotypes of patients hospitalized for an asthma exacerbation: prognostic implications. J Allergy Clin Immunol Pract. https://www.sciencedirect.com/science/article/pii/S2213219820310096?via%3Dihub
  13. Natasha Winter, Peter G Gibson, Michael Fricker, Jodie L Simpson, Peter AB Wark, Vanessa M McDonald. Hemopexin: a novel anti-inflammatory diagnostic marker in chronic airway disease. Allergy Asthma Immunol Res. https://e-aair.org/DOIx.php?id=10.4168/aair.2021.13.3.450
  14. Feng M, Zhang X, Wu WW, Chen ZH, Oliver BG, McDonald VM, Zhang HP, Xie M, Qin L, Zhang J, Wang L, Li WM, Wang G, Gibson PG. Clinical and Inflammatory Features of Exacerbation-Prone Asthma: A Cross-Sectional Study Using Multidimensional Assessment. Respiration. https://www.karger.com/Article/Abstract/510793
  15. Vanessa L Clark, Peter G Gibson, Vanessa M McDonald. What matters to people with severe asthma? Exploring add-on asthma medication and outcomes of importance. ERJ Open Research. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005593/
  16. Sarah A. Hiles, Peter G. Gibson, Alvar Agusti, Vanessa M. McDonald. Treatable Traits That Predict Health Status and Treatment Response in Airway Disease. J Allergy Clin Immunol Pract. https://www.sciencedirect.com/science/article/pii/S2213219820310965?via%3Dihub
  17. Shukla SD, Taylor SL, Gibson PG, Barker D, Upham JW, Yang IA, Reynolds PN, Hodge S, James AL, Rogers GB, Simpson JL. Add-on azithromycin reduces sputum cytokines in non-eosinophilic asthma: an AMAZES substudy. Thorax. https://thorax.bmj.com/content/76/7/733.long
  18. Bousquet J, Humbert M, Gibson PG, Kostikas K, Jaumont X, Pfister P, Nissen F. Real-world effectiveness of omalizumab in severe allergic asthma: a meta-analysis of observational studies. J Allergy Clin Immunol Pract. https://www.sciencedirect.com/science/article/pii/S2213219821000672
  19. Murphy VE, Jensen ME, Robijn AL, Wright TK, Mattes J, Collison A, Gibson PG. How Maternal BMI Modifies the Impact of Personalized Asthma Management in Pregnancy. J Allergy Clin Immunol Pract https://www.sciencedirect.com/science/article/pii/S2213219819306063?via%3Dihub
  20. LauraCordova-Rivera, Paul A.Gardiner, Peter G.Gibson, Elisabeth A.H.Winkler, Paola D.Urroz, Vanessa M.McDonald. Sedentary time in people with obstructive airway diseases. Respiratory Medicine. https://www.sciencedirect.com/science/article/pii/S0954611121000731
  21. Sarah A Hiles, Peter G Gibson, Vanessa M McDonald. Disease burden of eosinophilic airway disease: Comparing severe asthma, COPD and asthma–COPD overlap. https://onlinelibrary.wiley.com/doi/epdf/10.1111/resp.13841
  22. Wen Wen Wu, Xin Zhang, Min Li, Ying Liu, Zhi Hong Chen, Min Xie, Shu Zhen Zhao, Gang Wang, Hong Ping Zhang, Ting Wang, Ling Qin, Lei Wang, Brian G. Oliver, Hua Jing Wan, Jie Zhang, Vanessa M. McDonald, Guy B. Marks, Wei Min Li, Surinder S. Birring, Gang Wang, Peter G. Gibson. Treatable Traits in Elderly Asthmatics from the Australasian Severe Asthma Network: A Prospective Cohort Study JACI in Practice. https://www.sciencedirect.com/science/article/pii/S2213219821003871?via%3Dihub
  23. Chung LP, Upham JW, Bardin PG, Hew M. Rational oral corticosteroid use in adult severe asthma: A narrative review. Respirology. https://onlinelibrary.wiley.com/doi/10.1111/resp.13730
  24. Erin S Harvey , David Langton , Constance Katelaris, Sean Stevens , Claude S Farah, Andrew Gillman , John Harrington, Mark Hew , Vicky Kritikos, Naghmeh Radhakrishna , Philip Bardin , Matthew Peters , Paul N Reynolds , John W Upham , Melissa Baraket , Simon Bowler , Jeffrey Bowden, Jimmy Chien , Li Ping Chung, Christopher Grainge, Christine Jenkins , Gregory P Katsoulotos, Joy Lee , Vanessa M McDonald, Helen K Reddel , Janet Rimmer , Peter A B Wark, Peter G Gibson. Mepolizumab effectiveness and identification of super-responders in severe asthma. Eur Respir J. https://erj.ersjournals.com/content/55/5/1902420.long
  25. Hew M, McDonald VM, Bardin PG, Chung LP, Farah CS, Barnard A, Cooper MS, Gibson PG, Upham JW. Cumulative dispensing of high oral corticosteroid doses for treating asthma in Australia. Med J Aust. https://onlinelibrary.wiley.com/doi/10.5694/mja2.50758
  26. O’Neill C, Gibson PG, Heaney L, Upham JW, Yang I, Reynolds P, Hodge S, Jenkins C, Peters M, Marks GB, James AL, Simpson J. The cost-effectiveness of azithromycin in reducing exacerbations in uncontrolled asthma. Eur Respir J. https://erj.ersjournals.com/content/57/2/2002436.long